Psychotherapy and Emotion Research Laboratory

Department of Psychology                  Director: Stefan G. Hofmann, Ph.D
Boston University

Current Research

We are not currently recruiting participants for any active studies, nor have openings for volunteers or graduate students at this time.

Recently Completed Studies
Funding for these studies has been provided by the National Institute of Health/National Institute of Mental Health, the James S. McDonnell Foundation, and Boston University.  In addition to these studies, we conduct comprehensive literature reviews, meta-analyses, analyses of archival data, and analyses of epidemiological databases. For specific information about any of the projects, you may contact the person listed for each study.  To reach any of us by phone, please call (617) 353-9610.

Effect of D-Cycloserine on a Short Imagery Rescripting Intervention for Subclinical PTSD
The study aims to investigate the utility of d-cycloserine for enhancing the effect of a novel psychosocial intervention, imagery rescripting, for adults with mild to moderate PTSD symptoms after experiencing a traumatic event. All participants will receive either standard CBT or a newer form of CBT with imagery rescripting. To participate or for more information, please email or visit

Exploring Neural Mechanisms Underlying Positive Affect Training and Cognitive Behavioral Therapy Treatment Response in Individuals with Low Positive Affect 
In this study we are examining whether a novel mindfulness based intervention, Positive Affect Training (PAT), can enhance cognitive-behavioral therapy (CBT) for anxiety and low levels of happiness.  PAT includes the practice of mindfulness and loving-kindness meditation, which aims to increase positive affect and self-compassion. Recruitment for this study is now closed.

Boston Adolescent Neuroimaging of Depression and Anxiety (BANDA)

This study is funded by the NIMH (U01MH108168). In collaboration with MIT, Massachusetts General Hospital, and McLean Hospital, we are investigating structural and functional brain biomarkers related to anxiety and depression by collecting neuroimaging data and behavioral data from adolescents with depression and/or anxiety disorders, as well as healthy adolescents. Recruitment for this study is now closed.

From Defensive Responses to Clinical Interventions: Understanding the Mechanisms of Anxiety

This study is funded by the James S. McDonnell Foundation. The goal of this proposed Collaborative Award (in collaboration with Elizabeth Phelps and Joseph LeDoux at NYU) is to bring together basic scientists and clinician/scientists to promote the translation of basic research on the neural basis of emotion and defensive responses to the treatment of anxiety and related disorders.  

Generalized Anxiety Treatment Evaluation (GATE) Study

This study is funded by the NIH/NCCAM (R01AT007257). In collaboration with Massachusetts General Hospital, we are conducting a research study comparing the effectiveness of yoga, cognitive-behavioral therapy, and stress education in the treatment of generalized anxiety disorder. For more information, please visit, or email gate@bu.eduRecruitment for this study is now closed.

CBT Review
For a complete listing of all meta-analyses included in our recent CBT review, please click here.

Last updated: June 1, 2020